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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Naipctm1Kmma
targeted mutation 1, Kendle M Maslowski
MGI:5755386
Summary 2 genotypes


Genotype
MGI:5896660
cn1
Allelic
Composition
Naipctm1Kmma/Naipctm1Kmma
Lyz2tm1(cre)Ifo/Lyz2+
Genetic
Background
B6.Cg-Lyz2tm1(cre)Ifo Naipctm1Kmma
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyz2tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (41 available)
Naipctm1Kmma mutation (0 available); any Naipc mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
• mice treated with DSS exhibit a slight reduction of colitis in the early phase compared with control mice
• however, there is no protection after 9 days

neoplasm
N
• mice treated with azoxymethane and dextran sulfate sodium exhibit normal tumorigenesis

immune system
• mice treated with DSS exhibit a slight reduction of colitis in the early phase compared with control mice
• however, there is no protection after 9 days




Genotype
MGI:5896658
cn2
Allelic
Composition
Naipctm1Kmma/Naipctm1Kmma
Tg(Vil1-cre)997Gum/0
Genetic
Background
B6.Cg-Naipctm1Kmma Tg(Vil1-cre)997Gum
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Naipctm1Kmma mutation (0 available); any Naipc mutation (0 available)
Tg(Vil1-cre)997Gum mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• in mice treated with azoxymethane and dextran sulfate sodium

digestive/alimentary system
• mice treated with DSS exhibit reduced severity of colitis, weight loss and colon shortening compared with control mice

growth/size/body

homeostasis/metabolism
• in mice treated with azoxymethane and dextran sulfate sodium

immune system
• mice treated with DSS exhibit reduced severity of colitis, weight loss and colon shortening compared with control mice





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory