About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ccdc154ntl
new toothless
MGI:5702426
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ccdc154ntl/Ccdc154ntl involves: 129S7/SvEvBrd * C57BL/6J MGI:5702613


Genotype
MGI:5702613
hm1
Allelic
Composition
Ccdc154ntl/Ccdc154ntl
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die shortly after weaning
• however, mice fed a liquid diet survive

skeleton
• however, mice treated with fetal liver cell transplantation exhibit a rescue tooth eruption
• extensive odontoma-like proliferations around the malformed roots of the incisors in both the mandible and maxilla
• however, no molar-associated odontoma-like proliferations are observed
• lack of prominent bone marrow cavity
• with a club-shaped characteristics
• however, mice treated with fetal liver cell transplantation exhibit a rescue of various osteoporosis features

growth/size/body
• however, mice treated with fetal liver cell transplantation exhibit a rescue tooth eruption
• extensive odontoma-like proliferations around the malformed roots of the incisors in both the mandible and maxilla
• however, no molar-associated odontoma-like proliferations are observed
• varied severity among individuals
• varied severity among individuals

liver/biliary system
• varied severity among individuals

craniofacial
• however, mice treated with fetal liver cell transplantation exhibit a rescue tooth eruption
• extensive odontoma-like proliferations around the malformed roots of the incisors in both the mandible and maxilla
• however, no molar-associated odontoma-like proliferations are observed

hematopoietic system
• varied severity among individuals

immune system
• varied severity among individuals

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autosomal recessive osteopetrosis 1 DOID:0110942 OMIM:259700
J:226596





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/13/2021
MGI 6.16
The Jackson Laboratory