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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Smg1tm1b(EUCOMM)Hmgu
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5692718
Summary 2 genotypes


Genotype
MGI:6263527
hm1
Allelic
Composition
Smg1tm1b(EUCOMM)Hmgu/Smg1tm1b(EUCOMM)Hmgu
Genetic
Background
C57BL/6N-Smg1tm1b(EUCOMM)Hmgu/Wtsi
Cell Lines HEPD0860_6_F10
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smg1tm1b(EUCOMM)Hmgu mutation (1 available); any Smg1 mutation (174 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• small or absent trophoblast compartment at E9.5
• biased differentiation (diploid/polyploid trophoblast)

mortality/aging
• fewer than the expected numbers of embryos are obtained at E9.5




Genotype
MGI:6263526
ht2
Allelic
Composition
Smg1tm1b(EUCOMM)Hmgu/Smg1+
Genetic
Background
C57BL/6N-Smg1tm1b(EUCOMM)Hmgu/Wtsi
Cell Lines HEPD0860_6_F10
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smg1tm1b(EUCOMM)Hmgu mutation (1 available); any Smg1 mutation (174 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory