Phenotypes associated with this allele

• Allele Symbol: Nhlh2^{tm1b(KOMP)Mbp}
• Allele Name: targeted mutation 1b, Mouse Biology Program, UC Davis
• Allele ID: MGI:5637212
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nhlh2^tm1b(KOMP)Mbp/Nhlh2^tm1b(KOMP)Mbp	C57BL/6N-Nhlh2^tm1b(KOMP)Mbp/Tcp	MGI:5757419

Genotype
MGI:5757419

hm1

• Allelic Composition: Nhlh2^{tm1b(KOMP)Mbp}/Nhlh2^{tm1b(KOMP)Mbp}
• Genetic Background: C57BL/6N-Nhlh2^{tm1b(KOMP)Mbp}/Tcp
• Cell Lines: DEPD00525_4_D02

Data Sources

IMPC Data for Nhlh2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - UCD

cardiovascular system

eye hemorrhage ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

absent seminal vesicle ( J:211773 )

♂

IMPC - UCD

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

absent ovary ( J:211773 )

♀

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

absent testes ( J:211773 )

♂

IMPC - UCD

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - UCD

increased spleen weight ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased spleen weight ( J:211773 )

♂

IMPC - UCD

decreased mean corpuscular hemoglobin concentration ( J:211773 )

♀

IMPC - UCD

increased mean corpuscular volume ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - UCD

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - UCD

abnormal cholesterol homeostasis ( J:211773 )

♂

IMPC - UCD

immune system

increased spleen weight ( J:211773 )

♂

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♂

IMPC - UCD

renal/urinary system

decreased kidney weight ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

absent seminal vesicle ( J:211773 )

♂

IMPC - UCD

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

absent ovary ( J:211773 )

♀

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

absent testes ( J:211773 )

♂

IMPC - UCD

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

small uterus ( J:211773 )

♀

IMPC - UCD

abnormal epididymis morphology ( J:211773 )

♂

IMPC - UCD

absent epididymis ( J:211773 )

♂

IMPC - UCD

female infertility ( J:211773 )

♀

IMPC - UCD

male infertility ( J:211773 )

♂

IMPC - UCD

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - UCD

decreased bone mineral content ( J:211773 )

IMPC - UCD

decreased bone mineral density ( J:211773 )

IMPC - UCD

vision/eye

eye hemorrhage ( J:211773 )

IMPC - UCD