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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Wrap53tm1b(EUCOMM)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5637129
Summary 2 genotypes


Genotype
MGI:5767845
hm1
Allelic
Composition
Wrap53tm1b(EUCOMM)Wtsi/Wrap53tm1b(EUCOMM)Wtsi
Genetic
Background
C57BL/6N-Wrap53tm1b(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0638_5_A03
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wrap53tm1b(EUCOMM)Wtsi mutation (1 available); any Wrap53 mutation (28 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• unpatterned chorion
• branching morphology defect
• small or absent trophoblast compartment
• biased differentiation (diploid/polyploid trophoblast)

mortality/aging




Genotype
MGI:5797917
ht2
Allelic
Composition
Wrap53tm1b(EUCOMM)Wtsi/Wrap53+
Genetic
Background
C57BL/6N-Wrap53tm1b(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0638_5_A03
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wrap53tm1b(EUCOMM)Wtsi mutation (1 available); any Wrap53 mutation (28 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system

growth/size/body

homeostasis/metabolism





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory