Phenotypes associated with this allele

• Allele Symbol: Fbxo11^{tm2b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637115
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo11^tm2b(EUCOMM)Wtsi/Fbxo11^tm2b(EUCOMM)Wtsi	C57BL/6N-Fbxo11^tm2b(EUCOMM)Wtsi/H	MGI:6262425
ht2	Fbxo11^tm2b(EUCOMM)Wtsi/Fbxo11^+	C57BL/6N-Fbxo11^tm2b(EUCOMM)Wtsi/H	MGI:5797531

Genotype
MGI:6262425

hm1

• Allelic Composition: Fbxo11^{tm2b(EUCOMM)Wtsi}/Fbxo11^{tm2b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Fbxo11^{tm2b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0248_1_H03

Data Sources

IMPC Data for Fbxo11

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5797531

ht2

• Allelic Composition: Fbxo11^{tm2b(EUCOMM)Wtsi}/Fbxo11⁺
• Genetic Background: C57BL/6N-Fbxo11^{tm2b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0248_1_H03

Data Sources

IMPC Data for Fbxo11

behavior/neurological

hyperactivity ( J:211773 )

IMPC - HAR

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - HAR

decreased hematocrit ( J:211773 )

♂

IMPC - HAR

decreased hemoglobin content ( J:211773 )

IMPC - HAR

increased red blood cell distribution width ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - HAR

decreased circulating calcium level ( J:211773 )

IMPC - HAR

decreased circulating iron level ( J:211773 )

♀

IMPC - HAR

decreased circulating total protein level ( J:211773 )

♂

IMPC - HAR

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - HAR

skeleton

short tibia ( J:211773 )

♀

IMPC - HAR