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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Zfp318tm1.1Jhws
targeted mutation 1.1, John Weis
MGI:5606279
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Zfp318tm1.1Jhws/Zfp318tm1.1Jhws
Commd10Tg(Vav1-icre)A2Kio/Commd10+
B6.Cg-Zfp318tm1.1Jhws TgVav1-creA2Kio MGI:5606282


Genotype
MGI:5606282
cn1
Allelic
Composition
Zfp318tm1.1Jhws/Zfp318tm1.1Jhws
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background
B6.Cg-Zfp318tm1.1Jhws TgVav1-creA2Kio
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10Tg(Vav1-icre)A2Kio mutation (2 available); any Commd10 mutation (21 available)
Zfp318tm1.1Jhws mutation (1 available); any Zfp318 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• slight decrease in splenic T2 B cells in 4 week old mice
• decreased levels of IgD in transitional type 1 and 2 (T1,2), follicular (FO) and marginal zone (MZ) B cell populations
• increased levels of IgM in transitional type 2 (T2), follicular (FO) and marginal zone (MZ) B cell populations

hematopoietic system
• slight decrease in splenic T2 B cells in 4 week old mice
• decreased levels of IgD in transitional type 1 and 2 (T1,2), follicular (FO) and marginal zone (MZ) B cell populations
• increased levels of IgM in transitional type 2 (T2), follicular (FO) and marginal zone (MZ) B cell populations





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory