Analysis Tools
normal phenotype
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• females are viable and born at the expected ratios, develop normally and exhibit no obvious behavioral or physical phenotype and do not exhibit bone phenotypes
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Allele Symbol Allele Name Allele ID |
Txlngtm1.2Star targeted mutation 1.2, Rene St-Arnaud MGI:5605561 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• females are viable and born at the expected ratios, develop normally and exhibit no obvious behavioral or physical phenotype and do not exhibit bone phenotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• total cortical porosity is increased in the femoral mid-diaphysis
• percent closed porosity, reflecting osteocyte lacunae and intracortical resorption, is higher than in controls
• percent open porosity, reflecting vascular canals, is higher in mutant bones compared to controls
• however, mice show normal trabecular bone and femur biomechanical properties
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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