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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ifnktm1.1(KOMP)Vlcg
targeted mutation 1.1, Velocigene
MGI:5585587
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ifnktm1.1(KOMP)Vlcg/Ifnktm1.1(KOMP)Vlcg C57BL/6N-Ifnktm1.1(KOMP)Vlcg/J MGI:5797596
hm2
Ifnktm1.1(KOMP)Vlcg/Ifnktm1.1(KOMP)Vlcg C57BL/6NTac-Ifnktm1.1(KOMP)Vlcg MGI:7258013


Genotype
MGI:5797596
hm1
Allelic
Composition
Ifnktm1.1(KOMP)Vlcg/Ifnktm1.1(KOMP)Vlcg
Genetic
Background
C57BL/6N-Ifnktm1.1(KOMP)Vlcg/J
Cell Lines 10712A-A11
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifnktm1.1(KOMP)Vlcg mutation (1 available); any Ifnk mutation (14 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial

growth/size/body




Genotype
MGI:7258013
hm2
Allelic
Composition
Ifnktm1.1(KOMP)Vlcg/Ifnktm1.1(KOMP)Vlcg
Genetic
Background
C57BL/6NTac-Ifnktm1.1(KOMP)Vlcg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifnktm1.1(KOMP)Vlcg mutation (1 available); any Ifnk mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• reduced ear thickness, spleen weight, and inflammatory score with decreased macrophage, dendritic cell, and CD4+ and cD8+ T cell recruitment to the skin following IMQ treatment to induce psoriasis

immune system
• following IMQ treatment to induce psoriasis to a lesser extent than in wild-type mice
• reduced ear thickness, spleen weight, and inflammatory score with decreased macrophage, dendritic cell, and CD4+ and cD8+ T cell recruitment to the skin following IMQ treatment to induce psoriasis

growth/size/body
• following IMQ treatment to induce psoriasis to a lesser extent than in wild-type mice

hematopoietic system
• following IMQ treatment to induce psoriasis to a lesser extent than in wild-type mice





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory