All Phenotypes Pcdh15<tm1.1Ugds> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pcdh15^tm1.1Ugds
targeted mutation 1.1, Unite de Genetique des Deficits Sensoriels
MGI:5566900

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pcdh15^tm1.1Ugds/Pcdh15^tm1.1Ugds Myo15a^{tm1.1(cre)Ugds}/Myo15a⁺	involves: 129S1/SvImJ * C57BL/6J	MGI:5566905

Allelic Composition	Pcdh15^tm1.1Ugds/Pcdh15^tm1.1Ugds Myo15a^{tm1.1(cre)Ugds}/Myo15a⁺
Genetic Background	involves: 129S1/SvImJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo15a^{tm1.1(cre)Ugds} mutation (0 available); any Myo15a mutation (136 available)
Pcdh15^tm1.1Ugds mutation (0 available); any Pcdh15 mutation (132 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

abnormal cochlear hair bundle tip links morphology ( J:209275 )

decreased inner hair cell stereocilia number ( J:209275 )

short inner hair cell stereocilia ( J:209275 )

abnormal outer hair cell stereociliary bundle morphology ( J:209275 )

short outer hair cell stereocilia ( J:209275 )

decreased outer hair cell stereocilia number ( J:209275 )

abnormal hair cell mechanoelectric transduction ( J:209275 )

abnormal auditory brainstem response ( J:209275 )

increased or absent threshold for auditory brainstem response ( J:209275 )

abnormal cochlear nerve compound action potential ( J:209275 )

deafness ( J:209275 )

nervous system

abnormal cochlear hair bundle tip links morphology ( J:209275 )

decreased inner hair cell stereocilia number ( J:209275 )

short inner hair cell stereocilia ( J:209275 )

abnormal outer hair cell stereociliary bundle morphology ( J:209275 )

short outer hair cell stereocilia ( J:209275 )

decreased outer hair cell stereocilia number ( J:209275 )

abnormal hair cell mechanoelectric transduction ( J:209275 )

abnormal cochlear nerve compound action potential ( J:209275 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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