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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Exoc3l2tm1b(KOMP)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5548646
Summary 2 genotypes


Genotype
MGI:5757064
hm1
Allelic
Composition
Exoc3l2tm1b(KOMP)Wtsi/Exoc3l2tm1b(KOMP)Wtsi
Genetic
Background
C57BL/6N-Exoc3l2tm1b(KOMP)Wtsi/Wtsi
Cell Lines EPD0331_5_B02
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Exoc3l2tm1b(KOMP)Wtsi mutation (1 available); any Exoc3l2 mutation (3 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• labyrinth vascular defect at E14.5

embryo
• reduced cellular density of placenta at E14.5
• labyrinth vascular defect at E14.5

liver/biliary system

mortality/aging
IMPC - WTSI (J:211773)
MGI
• lethality at P14, with viable fetuses at E14.5 (J:261316)




Genotype
MGI:5757063
ht2
Allelic
Composition
Exoc3l2tm1b(KOMP)Wtsi/Exoc3l2+
Genetic
Background
C57BL/6N-Exoc3l2tm1b(KOMP)Wtsi/Wtsi
Cell Lines EPD0331_5_B02
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Exoc3l2tm1b(KOMP)Wtsi mutation (1 available); any Exoc3l2 mutation (3 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory