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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan
transgene insertion, Maike Sander
MGI:5501130
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan/0
Tg(Neurog3-cre)C1Able/0
involves: BALB/c * C57BL/6 MGI:5501184
cn2
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan/0
Tg(Gcg-cre)1Herr/0
involves: BALB/c * C57BL/6 * C57BL/6J * CBA/J MGI:5501185


Genotype
MGI:5501184
cn1
Allelic
Composition
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan/0
Tg(Neurog3-cre)C1Able/0
Genetic
Background
involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan mutation (0 available)
Tg(Neurog3-cre)C1Able mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• islet cell mass and proliferation are normal
• at the expense of other islet cell types

homeostasis/metabolism
N
• mice exhibit normal glucose tolerance




Genotype
MGI:5501185
cn2
Allelic
Composition
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan/0
Tg(Gcg-cre)1Herr/0
Genetic
Background
involves: BALB/c * C57BL/6 * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan mutation (0 available)
Tg(Gcg-cre)1Herr mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• mice do not exhibit reprogramed differentiation of non-beta endocrine cells into beta cells





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory