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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kdm6atm1.2Afst
targeted mutation 1.2, A Stewart
MGI:5499291
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Kdm6atm1.2Afst/Kdm6atm1.2Afst involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 MGI:5499568
ot2
Kdm6atm1.2Afst/Y involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 MGI:5499567


Genotype
MGI:5499568
hm1
Allelic
Composition
Kdm6atm1.2Afst/Kdm6atm1.2Afst
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6atm1.2Afst mutation (0 available); any Kdm6a mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

embryo
• some embryos have abnormal morphology at E8.5
• at E9.5 and E10.5

cardiovascular system
• cardiac malformations at E9.5

craniofacial
• at E9.5 and E10.5

growth/size/body
• at E9.5 and E10.5

skeleton
• at E9.5 and E10.5




Genotype
MGI:5499567
ot2
Allelic
Composition
Kdm6atm1.2Afst/Y
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6atm1.2Afst mutation (0 available); any Kdm6a mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are present at birth

embryo

cardiovascular system

growth/size/body

craniofacial
• in some mice at E9.5 and E13.5

skeleton
• in some mice at E9.5 and E13.5





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory