Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
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Dense nuclear cataracts in Gja8R205G/Gja8R205G and Gja8R205G/Gja8R205G Gja3tm1Scr/Gja3tm1Scr mice but degenerating peripheral lens fibers only in Gja8R205G/Gja8R205G mice
vision/eye
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• aberrant vacuole-like structures in the lens periphery
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
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Dense nuclear cataracts in heterozygous and homozygous Gja8R205G mice and microphthalmia in homozygotes
Allelic Composition |
Gja8R205G/Gja8R205G
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Genetic Background |
involves: 129S4/SvJae * CWD/LeAgl * SJL/J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
|
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vision/eye
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• aberrant vacuole-like structures or enlarged extracellular spaces in the peripheral regions
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• severely disrupted peripheral fiber cell organization with vacuoles and fiber degeneration
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
|
|
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
|
|
|
Dense nuclear cataracts in heterozygous and homozygous Gja8R205G mice and microphthalmia in homozygotes
Allelic Composition |
Gja8R205G/Gja8tm1Scr
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Genetic Background |
involves: 129S1/Sv * 129X1/SvJ * CWD/LeAgl * SJL/J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
Gja8tm1Scr mutation
(0 available);
any
Gja8 mutation
(33 available)
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Microphthalmia and small lenses with dense nuclear cataracts in Gja8R205G/Gja8tm1Scr mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja3tm1Scr mutation
(0 available);
any
Gja3 mutation
(17 available)
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
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Dense nuclear cataracts in Gja8R205G/Gja8R205G and Gja8R205G/Gja8R205G Gja3tm1Scr/Gja3tm1Scr mice but degenerating peripheral lens fibers only in Gja8R205G/Gja8R205G mice
vision/eye
N |
• mice exhibit normal lens periphery and lens fiber unlike in Gja8Nm2249 homozygotes
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Allelic Composition |
Gja8R205G/?
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Genetic Background |
involves: CWD/LeAgl * SJL/J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja8R205G mutation
(1 available);
any
Gja8 mutation
(33 available)
|
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