Mouse Genome Informatics
ht1
    Trp63tm1Cmis/Trp63+
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging

integument
• compromised desmosomes in the epidermis
• defects in cell-cell adhesion
• however, defects are alleviated by EGFR inhibition

craniofacial

digestive/alimentary system

growth/size

Mouse Models of Human Disease
OMIM IDRef(s)
Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate 106260 J:191121