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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(SOD1*A4V)A1073Gur
transgene insertion A1073, Mark E Gurney
MGI:5449884
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(SOD1)2Gur/0
Tg(SOD1*A4V)A1073Gur/0
involves: C57BL/6 * SJL MGI:5449900
tg2
Tg(SOD1*A4V)A1073Gur/0 involves: C57BL/6 * SJL MGI:5449885


Genotype
MGI:5449900
cx1
Allelic
Composition
Tg(SOD1)2Gur/0
Tg(SOD1*A4V)A1073Gur/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SOD1)2Gur mutation (2 available)
Tg(SOD1*A4V)A1073Gur mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• lifespan is on average 318.5 days

nervous system
• mutants exhibit protein aggregates in spinal cords
• mutants develop an amyotrophic lateral sclerosis-like phenotype, with an average onset of disease at 227.4 days

Mouse Models of Human Disease
OMIM ID Ref(s)
Amyotrophic Lateral Sclerosis 1; ALS1 105400 J:109458




Genotype
MGI:5449885
tg2
Allelic
Composition
Tg(SOD1*A4V)A1073Gur/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice appear normal and do not develop motor neuron disease (J:32665)





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory