Phenotypes associated with this allele

• Allele Symbol: Ndrg2^tm1.1Xzg
• Allele Name: targeted mutation 1.1, Xizhi Guo
• Allele ID: MGI:5441449
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ndrg2^tm1.1Xzg/Ndrg2^tm1.1Xzg	involves: 129S/SvEv * C57BL/6 * FVB/N	MGI:5441474
ht2	Ndrg2^tm1.1Xzg/Ndrg2^+	involves: 129S/SvEv * C57BL/6 * FVB/N	MGI:5441475

Genotype
MGI:5441474

hm1

• Allelic Composition: Ndrg2^tm1.1Xzg/Ndrg2^tm1.1Xzg
• Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal thoracic vertebrae morphology ( J:187603 )

• T9 is the transitional vertebra in 11 of 15 mice

thoracic vertebral transformation ( J:187603 )

• T13 to L1 transformation in 12 of 15 mice

lumbar vertebral transformation ( J:187603 )

• L6 to S1 transformation in 14 of 15 mice

sacral vertebral transformation ( J:187603 )

• S4 to S3 transformation in 14 of 15 mice

embryo

embryo phenotype ( J:187603 )

N • mice exhibit normal clock signaling in the paraxial mesoderm

Genotype
MGI:5441475

ht2

• Allelic Composition: Ndrg2^tm1.1Xzg/Ndrg2⁺
• Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

skeleton

abnormal thoracic vertebrae morphology ( J:187603 )

• T9 is the transitional vertebra in 6 of 17 mice

thoracic vertebral transformation ( J:187603 )

• T13 to L1 transformation in 7 of 17 mice

lumbar vertebral transformation ( J:187603 )

• L6 to S1 transformation in 14 of 17 mice

sacral vertebral transformation ( J:187603 )

• S4 to S3 transformation in 12 of 17 mice