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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Batf2tm1Kmm
targeted mutation 1, Kenneth Murphy
MGI:5435553
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Batf2tm1Kmm/Batf2tm1Kmm 129S6/SvEvTac-Batf2tm1Kmm MGI:5435558
cx2
 		Agtpbp1pcd-9J/Agtpbp1pcd-9J
Batf2tm1Kmm/Batf2tm1Kmm 		involves: 129S1/SvImJ * 129S6/SvEvTac MGI:5819377


Genotype
MGI:5435558
hm1
Allelic
Composition		 Batf2tm1Kmm/Batf2tm1Kmm
Genetic
Background		 129S6/SvEvTac-Batf2tm1Kmm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Batf2tm1Kmm mutation (1 available); any Batf2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to parasitic infection induced morbidity/mortality ( J:101977 )
• decreased survival after infection by Toxoplasma gondi.

mortality/aging
increased susceptibility to parasitic infection induced morbidity/mortality ( J:101977 )
• decreased survival after infection by Toxoplasma gondi.




Genotype
MGI:5819377
cx2
Allelic
Composition		 Agtpbp1pcd-9J/Agtpbp1pcd-9J
Batf2tm1Kmm/Batf2tm1Kmm
Genetic
Background		 involves: 129S1/SvImJ * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1pcd-9J mutation (1 available); any Agtpbp1 mutation (66 available)
Batf2tm1Kmm mutation (1 available); any Batf2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
ataxia ( J:238395 )
• homozygotes develop slight ataxia by 5 weeks of age and severe ataxia by 6 weeks of age




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory