About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Grm8tm1Dgen
targeted mutation 1, Deltagen
MGI:5427675
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Grm8tm1Dgen/Grm8tm1Dgen involves: 129P2/OlaHsd * C57BL/6J MGI:5427829


Genotype
MGI:5427829
hm1
Allelic
Composition
Grm8tm1Dgen/Grm8tm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm8tm1Dgen mutation (2 available); any Grm8 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• homozygous mutant animals displayed a statistically significant increase in total distance traveled in the open field test, relative to wild-type animals

nervous system
• homozygous mutant animals displayed a statistically significant decrease in Prepulse Inhibition (PPI) with a 100dB prepulse





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2022
MGI 6.19
The Jackson Laboratory