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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Apoetm2(APOE_i3)Yhg
targeted mutation 2, Yadong Huang
MGI:5427462
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Apoetm1Unc/Apoetm2(APOE_i3)Yhg
Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 MGI:5427501


Genotype
MGI:5427501
cx1
Allelic
Composition
Apoetm1Unc/Apoetm2(APOE_i3)Yhg
Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
Genetic
Background
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (33 available); any Apoe mutation (146 available)
Apoetm2(APOE_i3)Yhg mutation (0 available); any Apoe mutation (146 available)
Zbtb20Tg(PDGFB-APPSwInd)20Lms mutation (1 available); any Zbtb20 mutation (55 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• aged mice exhibit reduced amyloid plaques compared to Apoetm2(APOE_i3)Yhg/Apoetm2(APOE_i3)Yhg Tg(PDGFB-APPSwInd)20Lms mice

homeostasis/metabolism
• aged mice exhibit reduced amyloid plaques compared to Apoetm2(APOE_i3)Yhg/Apoetm2(APOE_i3)Yhg Tg(PDGFB-APPSwInd)20Lms mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory