Phenotypes associated with this allele

• Allele Symbol: Inhbb^tm1Grid
• Allele Name: targeted mutation 1, Tom Gridley
• Allele ID: MGI:5319783
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Inhbb^tm1Grid/Inhbb^tm1Grid	involves: 129S1/Sv * C57BL/6	MGI:5319784

Genotype
MGI:5319784

hm1

• Allelic Composition: Inhbb^tm1Grid/Inhbb^tm1Grid
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal maternal nurturing ( J:19647 )

♀ • females are more likely to neglect or consume their litters compared to controls

pup cannibalization ( J:19647 )

♀

vision/eye

corneal opacity ( J:19647 )

• develops with age in most mice born with open eyes

early eyelid opening ( J:19647 )

• about 40% of mice are born with open eyes

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:19647 )

• in 3 of 4 mice

• however, other liver enzyme levels are in the normal range