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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rhdtm1Goo
targeted mutation 1, Dominique Goossens
MGI:5318588
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rhdtm1Goo/Rhdtm1Goo involves: 129P2/OlaHsd * C57BL/6 MGI:5318590
cx2
Rhagtm1Goo/Rhagtm1Goo
Rhdtm1Goo/Rhdtm1Goo
involves: 129P2/OlaHsd * C57BL/6 MGI:5318591


Genotype
MGI:5318590
hm1
Allelic
Composition
Rhdtm1Goo/Rhdtm1Goo
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhdtm1Goo mutation (0 available); any Rhd mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• the alkalinisation rate constant values for ghosts are reduced by 30-40% compared to wild-type red blood cells
• basal adhesion to bEnd.3 endothelial cells is reduced

homeostasis/metabolism
• slightly increased at 17 weeks of age




Genotype
MGI:5318591
cx2
Allelic
Composition
Rhagtm1Goo/Rhagtm1Goo
Rhdtm1Goo/Rhdtm1Goo
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhagtm1Goo mutation (0 available); any Rhag mutation (10 available)
Rhdtm1Goo mutation (0 available); any Rhd mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
N
• not anaemic and show no obvious anomalies in standard haematological parameters or in erythrocyte morphology or fragility

homeostasis/metabolism
N
• no significant changes in iron, transferrin, or ferritin levels

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Rh-Null, Regulator Type; RHN 268150 J:182122





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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory