About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Thy1-APP*)2.2Ingm
transgene insertion 2.2, Ingenium Pharmaceuticals
MGI:5294353
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2+
Tg(Thy1-APP*)2.2Ingm/0
involves: C57BL/6 * DBA/1 MGI:5294359


Genotype
MGI:5294359
cx1
Allelic
Composition
Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2+
Tg(Thy1-APP*)2.2Ingm/0
Genetic
Background
involves: C57BL/6 * DBA/1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Thy1-APP*)2.2Ingm mutation (0 available)
Trib2Tg(Thy1-Trh/APP*)2.1Ingm mutation (0 available); any Trib2 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm
• neurodegeneration in the CA1 pyramidal cell layer
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm

behavior/neurological
• delayed
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm
• display cramping or tremors when lifted by the tail
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm

growth/size/body
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm

hematopoietic system
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm

immune system
• onset is later than in mice homozygous for Trib2Tg(Thy1-Trh/APP*)2.1Ingm

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:176575





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory