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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tctn2tm1.1Reit
targeted mutation 1.1, Jeremy Reiter
MGI:5292130
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tctn2tm1.1Reit/Tctn2tm1.1Reit involves: 129P2/OlaHsd * C57BL/6 MGI:5292219


Genotype
MGI:5292219
hm1
Allelic
Composition
Tctn2tm1.1Reit/Tctn2tm1.1Reit
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tctn2tm1.1Reit mutation (0 available); any Tctn2 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• cilia on limb bud mesenchyme are reduced in number compared to in control mice
• however, cilia morphology is normal
• cilia are scarse in the neural tube compared to in control mice
• neural tube cilia are short and bulbous unlike in control mice
• fully penetrant

nervous system
• cilia are scarse in the neural tube compared to in control mice
• neural tube cilia are short and bulbous unlike in control mice
• fully penetrant
• at E13.5

digestive/alimentary system

cardiovascular system

limbs/digits/tail
• cilia on limb bud mesenchyme are reduced in number compared to in control mice
• however, cilia morphology is normal
• bilateral or unilateral hindlimb

vision/eye

growth/size/body

craniofacial

cellular





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory