adipose tissue
|
• in all major fat depots
|
|
• at 3 months, white epididymal and subcutaneous fat contains only small immature adipocytes unlike in wild-type mice
|
|
• at 3 months, white epididymal fat contains only small immature adipocytes unlike in wild-type mice
|
|
• absent
|
|
• at 3 months, subcutaneous fat contains only small immature adipocytes unlike in wild-type mice
|
homeostasis/metabolism
|
• in a glucose or insulin tolerance test
• in fasted mice
|
|
• in fed mice
|
|
• only in fed mice
|
|
• in fasted mice
|
|
• from time to time
|
|
• in a glucose tolerance test, mice exhibit delayed glucose clearance compared with wild-type mice
|
|
• 200%
|
liver/biliary system
| N |
• mice do not exhibit steatohepatitis
(J:173404)
|
|
• 200%
|
|
• mainly macrovascular with some microvascular steatosis
|
immune system
growth/size
|
• until 6 weeks of age
|
hematopoietic system
integument
|
• at 3 months, subcutaneous fat contains only small immature adipocytes unlike in wild-type mice
|
cellular
|
• at 3 months, white epididymal and subcutaneous fat contains only small immature adipocytes unlike in wild-type mice
|
Mouse Models of Human Disease |
OMIM ID | Ref(s) | |
| Lipodystrophy, Congenital Generalized, Type 2; CGL2 | 269700 | J:173404 | |