Mouse Genome Informatics
hm1
    Bscl2tm1.2Gliu/Bscl2tm1.2Gliu
involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
adipose tissue
• in all major fat depots
• at 3 months, white epididymal and subcutaneous fat contains only small immature adipocytes unlike in wild-type mice
• at 3 months, white epididymal fat contains only small immature adipocytes unlike in wild-type mice
• at 3 months, subcutaneous fat contains only small immature adipocytes unlike in wild-type mice

homeostasis/metabolism
• in a glucose or insulin tolerance test
• in fasted mice
• from time to time
• in a glucose tolerance test, mice exhibit delayed glucose clearance compared with wild-type mice

liver/biliary system
N
• mice do not exhibit steatohepatitis (J:173404)
• mainly macrovascular with some microvascular steatosis

immune system

growth/size/body
• in all major fat depots
• until 6 weeks of age

hematopoietic system

integument
• at 3 months, subcutaneous fat contains only small immature adipocytes unlike in wild-type mice

cellular
• at 3 months, white epididymal and subcutaneous fat contains only small immature adipocytes unlike in wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Lipodystrophy, Congenital Generalized, Type 2; CGL2 269700 J:173404