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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Glt8d2tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007158
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Glt8d2tm1Lex/Glt8d2tm1Lex B6;129S5-Glt8d2tm1Lex/Mmucd MGI:5882202


Genotype
MGI:5882202
hm1
Allelic
Composition
Glt8d2tm1Lex/Glt8d2tm1Lex
Genetic
Background
B6;129S5-Glt8d2tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glt8d2tm1Lex mutation (2 available); any Glt8d2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• slightly reduced viability is observed

immune system
• decreased mean serum IgG1 and IgG2a responses to ovalbumin challenge
• decreased mean serum IgG1 and IgG2a responses to ovalbumin challenge

hematopoietic system
• decreased mean serum IgG1 and IgG2a responses to ovalbumin challenge
• decreased mean serum IgG1 and IgG2a responses to ovalbumin challenge





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory