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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Crispld2tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007091
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Crispld2tm1Lex/Crispld2tm1Lex B6;129S5-Crispld2tm1Lex/Mmucd MGI:5828261


Genotype
MGI:5828261
hm1
Allelic
Composition
Crispld2tm1Lex/Crispld2tm1Lex
Genetic
Background
B6;129S5-Crispld2tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crispld2tm1Lex mutation (2 available); any Crispld2 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• male homozygous mutant mice show enhanced glucose tolerance at all 3 time intervals tested

immune system
• homozygous mutant mice exhibit numerous immunological abnormalities when compared with controls
• homozygous mutant mice exhibit numerous immunological abnormalities when compared with controls

skeleton
• male homozygous mutant mice show notably decreased bone-related measurements when compared with controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory