Phenotypes associated with this allele

• Allele Symbol: Ikbke^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:5006718
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ikbke^tm1Dgen/Ikbke^tm1Dgen	B6.129P2-Ikbke^tm1Dgen	MGI:5006815

Genotype
MGI:5006815

hm1

• Allelic Composition: Ikbke^tm1Dgen/Ikbke^tm1Dgen
• Genetic Background: B6.129P2-Ikbke^tm1Dgen

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating glucose level ( J:171942 )

• when fed standard chow

• however, mice fed a high-fat diet exhibit normal serum glucose levels

decreased circulating leptin level ( J:171942 )

• when fed standard chow

increased insulin sensitivity ( J:171942 )

• when fed standard chow

• however, mice fed a high-fat diet exhibit normal insulin resistance

increased adiponectin level ( J:171942 )

• when fed a high-fat diet

growth/size/body

decreased susceptibility to weight gain ( J:171942 )

• when fed standard chow

• however, mice fed a high-fat diet exhibit normal weight gain