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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(PDGFB-APPSwDutLon)46Lpr
transgene insertion 46, Laurent Pradier
MGI:5003453
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(Hmgcr-PSEN1*M146L)#Lpr/0
Tg(PDGFB-APPSwDutLon)46Lpr/0
involves: C57BL/6 * CBA MGI:5003464
tg2
Tg(PDGFB-APPSwDutLon)46Lpr/0 involves: C57BL/6 * CBA MGI:5003463


Genotype
MGI:5003464
cx1
Allelic
Composition
Tg(Hmgcr-PSEN1*M146L)#Lpr/0
Tg(PDGFB-APPSwDutLon)46Lpr/0
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

homeostasis/metabolism
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:86694




Genotype
MGI:5003463
tg2
Allelic
Composition
Tg(PDGFB-APPSwDutLon)46Lpr/0
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• plaques are seen in mice over 18 months of age

homeostasis/metabolism
• plaques are seen in mice over 18 months of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:86694





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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory