Mouse Genome Informatics
cx1
    Tg(Hmgcr-PSEN1*M146L)#Lpr/0
Tg(PDGFB-APPSwDutLon)46Lpr/0

involves: C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
nervous system
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

other phenotype
• as soon as detectable, a large number of deposits have a fibrillar conformation
• plaques are seen at 6 months of age

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:86694


Mouse Genome Informatics
tg2
    Tg(PDGFB-APPSwDutLon)46Lpr/0
involves: C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
nervous system
• plaques are seen in mice over 18 months of age

other phenotype
• plaques are seen in mice over 18 months of age

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:86694