Mouse Genome Informatics
cn1
    Tg(Alb-TAg)#Arnd/0
C3Fe.Cg-Tg(Alb-TAg)#Arnd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
tumorigenesis
• mice treated with an adenovirus expressing cre exhibit massive multinodular hepatocellular carcinomas unlike control mice

Mouse Models of Human Disease
OMIM IDRef(s)
Hepatocellular Carcinoma 114550 J:171880


Mouse Genome Informatics
tg2
    Tg(Alb-TAg)#Arnd/0
(C3Fe.Cg-Tg(Alb-TAg)#Arnd x C57BL/6N)F1
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
immune system
• mice treated with an adenovirus expressing cre are tolerant to SV40 T antigen unlike control mice
• however, immunization with the agonistic peptide IVc-l breaks tolerance