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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fxntm1.1Pand
targeted mutation 1.1, Massimo Pandolfo
MGI:4881494
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Fxntm1.1Pand/Fxntm1Mkn B6.Cg-Fxntm1.1Pand Fxntm1Mkn/J MGI:6101473


Genotype
MGI:6101473
ht1
Allelic
Composition
Fxntm1.1Pand/Fxntm1Mkn
Genetic
Background
B6.Cg-Fxntm1.1Pand Fxntm1Mkn/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fxntm1.1Pand mutation (2 available); any Fxn mutation (30 available)
Fxntm1Mkn mutation (13 available); any Fxn mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit a mitochondrial biogenesis defect, with decreases in mitochondrial copy number in brain and skeletal muscle tissue

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Friedreich ataxia DOID:12705 OMIM:229300
OMIM:601992
J:242978





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory