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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Itpr3tm1(NCOM)Mfgc
targeted mutation 1, Mammalian Functional Genomics Centre
MGI:4880235
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Itpr3tm1(NCOM)Mfgc/Itpr3tm1(NCOM)Mfgc involves: C57BL/6J * C57BL/6N MGI:5532681


Genotype
MGI:5532681
hm1
Allelic
Composition
Itpr3tm1(NCOM)Mfgc/Itpr3tm1(NCOM)Mfgc
Genetic
Background
involves: C57BL/6J * C57BL/6N
Cell Lines N01293P1_C_239W_C5
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tm1(NCOM)Mfgc mutation (0 available); any Itpr3 mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in a 96 h two-bottle choice test, mice exhibit an increased preference for bottles with calcium chloride, calcium lactate, magnesium chloride, ammonium chloride and quinine hydrochloride compared to wild-type mice
• in a 96 h two-bottle choice test, mice preferred calcium chloride and calcium lactate to water unlike wild-type mice
• in a 96 h two-bottle choice test, mice exhibit reduced preference for saccharin compared with wild-type mice
• in a 96 h two-bottle choice test, mice exhibit a higher preference for denatonium, quinine hydrochloride, calcium chloride, calcium lactate, magnesium chloride and ammonium chloride compared with wild-type mice
• in a 96 h two-bottle choice test, mice exhibit a lower preference for saccharin, sucrose, maltose, polycose, monosodium glutamate, inosine monophosphate, trisodium pyrophosphate, zinc chloride, and potassium chloride compared with wild-type mice
• in a 96 h two-bottle choice test, mice exhibit reduced preference for saccharin compared with wild-type mice
• in a 96 h two-bottle choice test, mice exhibit a lower preference for saccharin, sucrose, maltose and polycose compared with wild-type mice

taste/olfaction
• in a 96 h two-bottle choice test, mice exhibit an increased preference for bottles with calcium chloride, calcium lactate, magnesium chloride, ammonium chloride and quinine hydrochloride compared to wild-type mice
• in a 96 h two-bottle choice test, mice preferred calcium chloride and calcium lactate to water unlike wild-type mice
• in a 96 h two-bottle choice test, mice exhibit reduced preference for saccharin compared with wild-type mice
• in a 96 h two-bottle choice test, mice exhibit a higher preference for denatonium, quinine hydrochloride, calcium chloride, calcium lactate, magnesium chloride and ammonium chloride compared with wild-type mice
• in a 96 h two-bottle choice test, mice exhibit a lower preference for saccharin, sucrose, maltose, polycose, monosodium glutamate, inosine monophosphate, trisodium pyrophosphate, zinc chloride, and potassium chloride compared with wild-type mice





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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory