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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ptbp1tm1Msol
targeted mutation 1, Michele Solimena
MGI:4868473
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ptbp1tm1Msol/Ptbp1tm1Msol B6J.129-Ptbp1tm1Msol MGI:5693895


Genotype
MGI:5693895
hm1
Allelic
Composition
Ptbp1tm1Msol/Ptbp1tm1Msol
Genetic
Background
B6J.129-Ptbp1tm1Msol
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptbp1tm1Msol mutation (0 available); any Ptbp1 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Small size of Ptbp1tm1Msol/Ptbp1tm1Msol embryos

mortality/aging

embryo
• very few embryos exhibit partial separation of cell layers
• absence of squamous endodermal cells at E7.5
• embryos are not able to begin cavitation or properly form the yolk sac and the ectoplacental cone
• does not form properly
• membrane is not properly formed and contains an unusual amount of eosinophilic material
• in some mice, the yolk sac does not clearly separate from the epiblast
• delayed formation

growth/size/body

cellular
• in E7.5 embryos
• in E7.5 embryos





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory