Phenotypes associated with this allele

• Allele Symbol: Pcid2^tm1Imku
• Allele Name: targeted mutation 1, Nobuo Sakaguchi
• Allele ID: MGI:4843141
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pcid2^tm1Imku/Pcid2^tm1Imku Cd19^tm1(cre)Cgn/Cd19^+	involves: 129P2/OlaHsd * C57BL/6 * CBA	MGI:4843145

Genotype
MGI:4843145

cn1

• Allelic Composition: Pcid2^tm1Imku/Pcid2^tm1Imku; Cd19^tm1(cre)Cgn/Cd19⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased mature B cell number ( J:166080 )

• severely reduced numbers of splenic B cells in the T1(Cd21^loCd24^hi) and T2 (Cd21^hiCd24^hi) stages

• B220+ cells markedly reduced, particularly in the follicular regions of the spleen

decreased follicular B cell number ( J:166080 )

• reduced numbers of Cd21^intCd24^lo cells

decreased marginal zone B cell number ( J:166080 )

• reduced numbers of Cd21^hiCd23^lo cells

abnormal spleen B cell follicle morphology ( J:166080 )

• reduced follicular region size

hematopoietic system

decreased mature B cell number ( J:166080 )

• severely reduced numbers of splenic B cells in the T1(Cd21^loCd24^hi) and T2 (Cd21^hiCd24^hi) stages

• B220+ cells markedly reduced, particularly in the follicular regions of the spleen

decreased follicular B cell number ( J:166080 )

• reduced numbers of Cd21^intCd24^lo cells

decreased marginal zone B cell number ( J:166080 )

• reduced numbers of Cd21^hiCd23^lo cells

abnormal spleen B cell follicle morphology ( J:166080 )

• reduced follicular region size