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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mir33tm1.1Koho
targeted mutation 1.1, Koh Ono
MGI:4837623
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mir33tm1.1Koho/Mir33tm1.1Koho involves: C57BL/6 MGI:4837624


Genotype
MGI:4837624
hm1
Allelic
Composition
Mir33tm1.1Koho/Mir33tm1.1Koho
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir33tm1.1Koho mutation (0 available); any Mir33 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increase in APOA1 mediated cholesterol efflux in peritoneal macrophages
• increase in total cholesterol at 16 weeks of age
• at 16 weeks of age
• increase is more prominent in females than in males
• increased levels of HDL are mainly composed of mature HDL (very large, large, and medium HDL)

immune system
• increase in APOA1 mediated cholesterol efflux in peritoneal macrophages

hematopoietic system
• increase in APOA1 mediated cholesterol efflux in peritoneal macrophages





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory