About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Smn1tm1.1Dscd
targeted mutation 1.1, Dawn S Chandler
MGI:4836979
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Smn1tm1.1Dscd/Smn1tm1.1Dscd involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 MGI:4836985
ht2
Smn1tm1Msd/Smn1tm1.1Dscd involves: 129S/SvEv * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 MGI:4836986


Genotype
MGI:4836985
hm1
Allelic
Composition
Smn1tm1.1Dscd/Smn1tm1.1Dscd
Genetic
Background
involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smn1tm1.1Dscd mutation (0 available); any Smn1 mutation (86 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

muscle
• at 60 days, mice exhibit an increase in larger-sized fibers compared with wild-type mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
juvenile spinal muscular atrophy DOID:12376 OMIM:253400
J:164889




Genotype
MGI:4836986
ht2
Allelic
Composition
Smn1tm1Msd/Smn1tm1.1Dscd
Genetic
Background
involves: 129S/SvEv * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smn1tm1.1Dscd mutation (0 available); any Smn1 mutation (86 available)
Smn1tm1Msd mutation (37 available); any Smn1 mutation (86 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

nervous system
N
• mice exhibit normal neuromuscular junctions morphology and neuromuscular transmissions





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory