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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Stim1tm1.1Kuro
targeted mutation 1.1, Tomohiro Kurosaki
MGI:4821943
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Stim1tm1.1Kuro/Stim1tm1.1Kuro C57BL/6-Stim1tm1.1Kuro MGI:4821950
ht2
Stim1tm1.1Kuro/Stim1+ C57BL/6-Stim1tm1.1Kuro MGI:4821952


Genotype
MGI:4821950
hm1
Allelic
Composition
Stim1tm1.1Kuro/Stim1tm1.1Kuro
Genetic
Background
C57BL/6-Stim1tm1.1Kuro
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Kuro mutation (0 available); any Stim1 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die perinatally
• embryos are apparently normal at E18.5

growth/size/body
• mice born alive are slightly reduced in size

respiratory system
• mice born alive die within 1 day of apparent respiratory failure

immune system
• liver mast cell degranulation induced by ionomycin is reduced
• by liver mast cells
• by liver mast cells

hematopoietic system
• liver mast cell degranulation induced by ionomycin is reduced

cellular
• liver mast cell degranulation induced by ionomycin is reduced




Genotype
MGI:4821952
ht2
Allelic
Composition
Stim1tm1.1Kuro/Stim1+
Genetic
Background
C57BL/6-Stim1tm1.1Kuro
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Kuro mutation (0 available); any Stim1 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• passive cutaneous anaphylaxis is reduced





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory