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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dll1m1Mhda
mutation 1, Martin Hrabe de Angelis
MGI:4821259
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dll1m1Mhda/Dll1m1Mhda C3HeB/FeJ-Dll1m1Mhda MGI:4821282
ht2
Dll1m1Mhda/Dll1+ C3HeB/FeJ-Dll1m1Mhda MGI:4821283


Genotype
MGI:4821282
hm1
Allelic
Composition
Dll1m1Mhda/Dll1m1Mhda
Genetic
Background
C3HeB/FeJ-Dll1m1Mhda
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1m1Mhda mutation (1 available); any Dll1 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• only 32% of expected mice are alive after weaning

growth/size/body




Genotype
MGI:4821283
ht2
Allelic
Composition
Dll1m1Mhda/Dll1+
Genetic
Background
C3HeB/FeJ-Dll1m1Mhda
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1m1Mhda mutation (1 available); any Dll1 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most mice die or are sacrificed within the first months of life

cardiovascular system
• non-significant trend

homeostasis/metabolism

growth/size/body
• in female mice

behavior/neurological
• in female mice

skeleton
• whole body bone mineral content is reduced compared to in wild-type mice
• whole body bone mineral density is reduced compared to in wild-type mice

adipose tissue

immune system
N
• mice exhibit normal levels of CD19+ and CD4+ cells





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory