All Phenotypes Gt(ROSA)26Sor<tm2(Foxo1)Jnk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gt(ROSA)26Sor^{tm2(Foxo1)Jnk}
targeted mutation 2, Jun Nakae
MGI:4820847

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^{tm2(Foxo1)Jnk}/Gt(ROSA)26Sor⁺ Pdpk1^tm1Maka/Pdpk1^tm1Maka Tg(CAG-cat,-lacZ)11Miya/0 Tg(Pomc1-cre)16Lowl/0	involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N	MGI:4820872

Allelic Composition	Gt(ROSA)26Sor^{tm2(Foxo1)Jnk}/Gt(ROSA)26Sor⁺ Pdpk1^tm1Maka/Pdpk1^tm1Maka Tg(CAG-cat,-lacZ)11Miya/0 Tg(Pomc1-cre)16Lowl/0
Genetic Background	involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm2(Foxo1)Jnk} mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
Pdpk1^tm1Maka mutation (0 available); any Pdpk1 mutation (138 available)
Tg(CAG-cat,-lacZ)11Miya mutation (0 available)
Tg(Pomc1-cre)16Lowl mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

increased total body fat amount ( J:162892 )

• female mice exhibit a tended towards increased adiposity compared with wild-type mice

behavior/neurological

increased food intake ( J:162892 )

• mice exhibit increased food intake compared with wild-type mice and Pdpk1^tm1Maka/Pdpk1^tm1Maka Tg(CAG-cat-lacZ)11Miya Tg(Pomc1-cre)16Lowl mice

growth/size/body

increased body weight ( J:162892 )

• at 16 weeks, mice are significantly heavier than Pdpk1^tm1Maka/Pdpk1^tm1Maka Tg(CAG-cat-lacZ)11Miya Tg(Pomc1-cre)16Lowl mice

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