Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kidins220tm1.1Mvc mutation
(0 available);
any
Kidins220 mutation
(79 available)
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Allelic
Composition |
Kidins220tm1.1Mvc/Kidins220+
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Genetic
Background |
involves: 129S1/Sv * C57BL/6 |
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kidins220tm1.1Mvc mutation
(0 available);
any
Kidins220 mutation
(79 available)
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nervous system
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• between 1 and 3 months, mice fail to exhibit an increase in dendritic complexity in the barrel somatosensory cortex unlike in wild-type mice
• at 3 months, mice exhibit decreased dendritic complexity in the dentate gyrus compared with wild-type mice
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kidins220tm1.1Mvc mutation
(0 available);
any
Kidins220 mutation
(79 available)
Tg(Thy1-YFP)HJrs mutation
(3 available)
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nervous system
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• in vivo, dendritic spines of pyramidal neurons are less stable than spines on wild-type cells
• however, spine formation rate is normal
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Analysis Tools