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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Myh6-TNNT2*R141W)#Ajm
transgene insertion, Ali J Marian
MGI:4819721
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Myh6-TNNT2*R141W)#Ajm/0 involves: C3H * C57BL/6 * ICR MGI:4819724


Genotype
MGI:4819724
tg1
Allelic
Composition
Tg(Myh6-TNNT2*R141W)#Ajm/0
Genetic
Background
involves: C3H * C57BL/6 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 29% of mice die within 1 year and almost all die by 2 years of age

cardiovascular system
• increase in the ventricular weight to body weight ratio compared to age and sex matched controls
• increase in expression of markers of cardiac hypertrophy
• increase in left ventricular end systolic and end diastolic diameters
• increase in the collagen volume fraction
• decrease in left ventricular systolic function

Mouse Models of Human Disease
OMIM ID Ref(s)
Cardiomyopathy, Dilated, 1D; CMD1D 601494 J:161899





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory