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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Tnnt2-TNNT2*R92Q)M-2Ajm
transgene insertion M-2, Ali J Marian
MGI:4819719
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Tnnt2-TNNT2*R92Q)M-2Ajm/0 involves: C3H * C57BL/6 * ICR MGI:4819727


Genotype
MGI:4819727
tg1
Allelic
Composition
Tg(Tnnt2-TNNT2*R92Q)M-2Ajm/0
Genetic
Background
involves: C3H * C57BL/6 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• cardiomyocyte disarray (J:117554)
• this line displays the most extensive disarray relative to other lines carrying the same transgene (J:117554)
• cardiomyocyte disarray (J:117554)
• this line displays the most extensive disarray relative to other lines carrying the same transgene (J:117554)
• increase in interstitial collagen (J:117554)
• increase in interstitial collagen (J:117554)
• the decrease in the ratio of peak early velocity to peak atrial velocity is indicative of left ventricular diastolic dysfunction (J:117554)
• the decrease in the ratio of peak early velocity to peak atrial velocity is indicative of left ventricular diastolic dysfunction (J:117554)
• increase in mitral valve peak atrial velocity and a decrease in the ratio of peak early velocity to peak atrial velocity compared to controls (J:117554)
• increase in mitral valve peak atrial velocity and a decrease in the ratio of peak early velocity to peak atrial velocity compared to controls (J:117554)

muscle
• cardiomyocyte disarray (J:117554)
• this line displays the most extensive disarray relative to other lines carrying the same transgene (J:117554)
• cardiomyocyte disarray (J:117554)
• this line displays the most extensive disarray relative to other lines carrying the same transgene (J:117554)

Mouse Models of Human Disease
OMIM ID Ref(s)
Cardiomyopathy, Familial Hypertrophic, 2; CMH2 115195 J:117554





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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory