cardiovascular system

abnormal myocardial fiber morphology ( J:117554 )

• cardiomyocyte disarray

• this line displays the most extensive disarray relative to other lines carrying the same transgene

cardiac interstitial fibrosis ( J:117554 )

• increase in interstitial collagen

• the decrease in the ratio of peak early velocity to peak atrial velocity is indicative of left ventricular diastolic dysfunction

abnormal blood flow velocity ( J:117554 )

• increase in mitral valve peak atrial velocity and a decrease in the ratio of peak early velocity to peak atrial velocity compared to controls

muscle

abnormal myocardial fiber morphology ( J:117554 )

• cardiomyocyte disarray

• this line displays the most extensive disarray relative to other lines carrying the same transgene

Mouse Models of Human Disease		OMIM ID	Ref(s)
Cardiomyopathy, Familial Hypertrophic, 2; CMH2		115195	J:117554