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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lrrk2tm3.1Shn
targeted mutation 3.1, Jie Shen
MGI:4460961
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Lrrk2tm3.1Shn/Lrrk2tm3.1Shn involves: 129 * C57BL/6 MGI:4460975


Genotype
MGI:4460975
hm1
Allelic
Composition
Lrrk2tm3.1Shn/Lrrk2tm3.1Shn
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrk2tm3.1Shn mutation (1 available); any Lrrk2 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• at 20 months, kidneys appear rough and granular, are smaller, weigh less, and are darker than in wild-type mice
• however, kidneys are normal at 10 weeks
• at 20 months
• at 20 months
• in aged mice
• at 20 months

nervous system
N
• mice exhibit normal dopaminergic neurons and dopamine turnover





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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory