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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Spns2tm1a(KOMP)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4460276
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi B6JTyr;B6N-Spns2tm1a(KOMP)Wtsi/Wtsi MGI:5781762
hm2
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi C57BL/6-Spns2tm1a(KOMP)Wtsi MGI:5442811


Genotype
MGI:5781762
hm1
Allelic
Composition
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic
Background
B6JTyr;B6N-Spns2tm1a(KOMP)Wtsi/Wtsi
Cell Lines EPD0090_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spns2tm1a(KOMP)Wtsi mutation (1 available); any Spns2 mutation (11 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system

hematopoietic system

vision/eye
IMPC - WTSI
IMPC - WTSI
IMPC - WTSI

skeleton

cardiovascular system

pigmentation

behavior/neurological
IMPC - WTSI




Genotype
MGI:5442811
hm2
Allelic
Composition
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic
Background
C57BL/6-Spns2tm1a(KOMP)Wtsi
Cell Lines EPD0090_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spns2tm1a(KOMP)Wtsi mutation (1 available); any Spns2 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• macrophage exhibit normal responses to inflammatory stimuli
• mice exhibit normal early B cell development
• circulating
• in the peritoneal cavity
• in response to immune challenge
• in response to immune challenge

vision/eye

pigmentation

hematopoietic system
• circulating
• in the peritoneal cavity
• in response to immune challenge
• in response to immune challenge





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory