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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Spns2tm1a(KOMP)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4460276
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi C57BL/6-Spns2tm1a(KOMP)Wtsi MGI:5442811
hm2
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi Not Specified MGI:5450240
hm3
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi Not Specified MGI:5450669
ot4
Spns2tm1a(KOMP)Wtsi/? Not Specified MGI:5450241


Genotype
MGI:5442811
hm1
Allelic
Composition
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic
Background
C57BL/6-Spns2tm1a(KOMP)Wtsi
Cell Lines EPD0090_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spns2tm1a(KOMP)Wtsi mutation (1 available); any Spns2 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal early B cell development
• macrophage exhibit normal responses to inflammatory stimuli
• circulating
• in the peritoneal cavity
• in response to immune challenge
• in response to immune challenge

vision/eye

pigmentation

hematopoietic system
• circulating
• in the peritoneal cavity
• in response to immune challenge
• in response to immune challenge




Genotype
MGI:5450240
hm2
Allelic
Composition
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic
Background
Not Specified
Cell Lines EPD0090_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spns2tm1a(KOMP)Wtsi mutation (1 available); any Spns2 mutation (11 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system

hematopoietic system

homeostasis/metabolism

immune system

pigmentation

vision/eye




Genotype
MGI:5450669
hm3
Allelic
Composition
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spns2tm1a(KOMP)Wtsi mutation (1 available); any Spns2 mutation (11 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype



Genotype
MGI:5450241
ot4
Allelic
Composition
Spns2tm1a(KOMP)Wtsi/?
Genetic
Background
Not Specified
Cell Lines EPD0090_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spns2tm1a(KOMP)Wtsi mutation (1 available); any Spns2 mutation (11 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory