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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Scpep1tm1Jomm
targeted mutation 1, Joseph M Miano
MGI:4437862
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Scpep1tm1Jomm/Scpep1tm1Jomm involves: 129S/SvEvBrd * C57BL/6 MGI:4437884


Genotype
MGI:4437884
hm1
Allelic
Composition		 Scpep1tm1Jomm/Scpep1tm1Jomm
Genetic
Background		 involves: 129S/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scpep1tm1Jomm mutation (1 available); any Scpep1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal vascular wound healing ( J:158052 )
• ollowing arterial ligation, mice exhibit attenuated neointimal formation, decreased area bound by external elastic lamina, and decreased intimal and medial cell proliferation compared to in similarly treated wild-type mice
• however, apoptosis following arterial ligation is normal

homeostasis/metabolism
abnormal vascular wound healing ( J:158052 )
• ollowing arterial ligation, mice exhibit attenuated neointimal formation, decreased area bound by external elastic lamina, and decreased intimal and medial cell proliferation compared to in similarly treated wild-type mice
• however, apoptosis following arterial ligation is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory