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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nek9tm1a(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4433670
Summary 2 genotypes


Genotype
MGI:5706046
hm1
Allelic
Composition
Nek9tm1a(EUCOMM)Wtsi/Nek9tm1a(EUCOMM)Wtsi
Genetic
Background
C57BL/6N-Nek9tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0419_4_B09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nek9tm1a(EUCOMM)Wtsi mutation (1 available); any Nek9 mutation (32 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• labyrinth vascular defect at E14.5
• hemorrhagic areas/blood pools are seen in the E14.5 placenta

embryo
• hemorrhagic areas/blood pools are seen in the E14.5 placenta
• reduced cellular density at E14.5
• labyrinth vascular defect at E14.5
• small placenta at E14.5
• small or absent trophoblast compartment at E9.5

mortality/aging




Genotype
MGI:5706045
ht2
Allelic
Composition
Nek9tm1a(EUCOMM)Wtsi/Nek9+
Genetic
Background
C57BL/6N-Nek9tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0419_4_B09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nek9tm1a(EUCOMM)Wtsi mutation (1 available); any Nek9 mutation (32 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism

immune system

integument





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory