Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ehmt1tm1.1Tara mutation
(0 available);
any
Ehmt1 mutation
(90 available)
Myf5tm3(cre)Sor mutation
(1 available);
any
Myf5 mutation
(17 available)
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ehmt1tm1.1Tara mutation
(0 available);
any
Ehmt1 mutation
(90 available)
Ehmt2tm1.1Tara mutation
(0 available);
any
Ehmt2 mutation
(55 available)
Tg(Camk2a-cre)2Gsc mutation
(2 available)
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behavior/neurological
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• travel significantly less than control mice in a new environment
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• reduction in vertical episodes in a new environment
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• travel significantly less than control mice in a new environment
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ehmt1tm1.1Tara mutation
(0 available);
any
Ehmt1 mutation
(90 available)
Tg(Camk2a-cre)2Gsc mutation
(2 available)
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nervous system
N |
• the specific neuronal cell architecture in the striatum and the hippocampus is not altered
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behavior/neurological
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• almost completely lack a preference for sucrose
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• do not remember their negative experience
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• do not remember their negative experience
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• starting around 6-8 weeks of age in an open field make fewer total arm entries in an elevated plus maze
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• almost completely lack a preference for sucrose
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• make more entries into and spend more time in open arms in an elevated plus maze
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• slightly improved performance in some trials during standard accelerated rotarod analysis
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growth/size/body
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• almost double the body weight as compared to controls by 5-6 months of age
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ehmt1tm1.1Tara mutation
(0 available);
any
Ehmt1 mutation
(90 available)
Tg(Adipoq-cre)1Evdr mutation
(3 available)
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homeostasis/metabolism
adipose tissue
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• reduced fatty-acid oxidation capacity and fatty acid uptake in brown adipose tissue
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growth/size/body
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• without a change in food intake
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liver/biliary system
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• higher amounts of lipids
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cellular
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• reduced fatty-acid oxidation capacity in brown adipose tissue
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