Mouse Genome Informatics
hm1
     Sdhdtm1Jpb/Sdhdtm1Jpb
129P2/OlaHsd-Sdhdtm1Jpb
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
mortality/aging
complete embryonic lethality ( J:155380 )
• die before E10.5


Mouse Genome Informatics
ht2
     Sdhdtm1Jpb/Sdhd+
either: 129P2/OlaHsd-Sdhdtm1Jpb or (involves: 129P2/OlaHsd * C57BL/6J)
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:155380 )
• viable and fertile with no indications of paraganglioma or pheochromocytoma and no abnormalities detected in the carotid body or adrenal medulla at any age in contrast to expectations from human disease data

Mouse Models of Human Disease
 OMIM IDRef(s)
NOT Paragangliomas 4; PGL4 115310 J:155380


Mouse Genome Informatics
cx3
     H19tm1Tilg/H19+
Sdhdtm1Jpb/Sdhd+
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
tumorigenesis
tumorigenesis ( J:155380 )
N
• no paragangliomas nor pheochromocytomas are detected in mice at up to 29 months of age in contrast to expectations from human disease data (J:155380)

nervous system
nervous system phenotype ( J:155380 )
N
• no significant changes in carotid body or the adrenal medulla are seen (J:155380)