All Phenotypes Ntsr1<tm1Pang> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ntsr1^tm1Pang
targeted mutation 1, Zhen Pang
MGI:4418203

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ntsr1^tm1Pang/Ntsr1^tm1Pang	C57BL/6-Ntsr1^tm1Pang	MGI:4418207

Allelic Composition	Ntsr1^tm1Pang/Ntsr1^tm1Pang
Genetic Background	C57BL/6-Ntsr1^tm1Pang

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntsr1^tm1Pang mutation (0 available); any Ntsr1 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal startle reflex ( J:155775 )

• unaffected by treatment with PD149163 in contrast to decreased responses in controls

decreased startle reflex ( J:155775 )

• males treated with amphetamine have reduced startle responses whereas females show no affect

• startle responses are lower in both sexes after treatment with dizocilpine except at the highest doses

nervous system

abnormal prepulse inhibition ( J:155775 )

• unaffected by PD149163 in contrast to controls which display increased prepulse inhibition

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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