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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Foxa2tm1.1Stf
targeted mutation 1.1, Markus Stoffel
MGI:4417942
Summary 2 genotypes


Genotype
MGI:4417950
cn1
Allelic
Composition
Foxa2tm1.1Stf/Foxa2tm1.1Stf
Genetic
Background
B6.129-Foxa2tm1.1Stf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxa2tm1.1Stf mutation (0 available); any Foxa2 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• when injected with cre-expressing adenovirus
• when injected with cre-expressing adenovirus
• 4-fold compared to in wild-type mice

homeostasis/metabolism
• when injected with cre-expressing adenovirus
• when injected with cre-expressing adenovirus




Genotype
MGI:4417949
cn2
Allelic
Composition
Foxa2tm1.1Stf/Foxa2tm1.1Stf
Tg(Nes-cre)1Kln/0
Genetic
Background
B6.Cg-Foxa2tm1.1Stf Tg(Nes-cre)1Kln
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxa2tm1.1Stf mutation (0 available); any Foxa2 mutation (26 available)
Tg(Nes-cre)1Kln mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in fed mice and mice fed a high fat diet
• in fasting mice and mice fed a high fat diet
• in mice fed regular chow or a high fat diet
• glucose clearance is modestly increased compared to in wild-type mice
• indicated by reduced fasting plasma insulin and free fatty acid

behavior/neurological
• in mice fed a high fat diet
• in mice fed regular chow or a high fat diet

adipose tissue
• in mice fed regular chow or a high fat diet

growth/size/body
• in mice fed regular chow or a high fat diet





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory